Metacam injection for dogs

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Warning: Repeated use of meloxicam in cats has been associated with acute renal failure and death. Do not administer additional injectable or oral meloxicam to cats. See ContraindicationsWarningsand Precautions for detailed information. Each mL of this sterile product for injection contains meloxicam 5.

Carefully consider the potential benefits and risk of Metacam and other treatment options before deciding to use Metacam. Use the lowest effective dose for the shortest duration consistent with individual response.

metacam injection for dogs

Not for use in humans. Keep this and all medications out of reach of children. Consult a physician in case of accidental ingestion by humans. For IV or SQ injectable use in dogs. Appropriate laboratory testing to establish hematological and serum biochemical baseline data is recommended prior to, and periodically during use of any NSAID in dogs.

Owner should be advised to observe their dogs for signs of potential drug toxicity. Meloxicam is not recommended for use in dogs with bleeding disorders, as safety has not been established in dogs with these disorders.

Safety has not been established for intramuscular IM administration in dogs. As a class, cyclo-oxygenase inhibitory NSAIDs may be associated with gastrointestinal, renal and hepatic toxicity. Sensitivity to drug-associated adverse events varies with the individual patient. Concurrent administration of potentially nephrotoxic drugs should be carefully approached. NSAIDs may inhibit the prostaglandins that maintain normal homeostatic function. Such anti-prostaglandin effects may result in clinically significant disease in patients with underlying or preexisting disease that has not been previously diagnosed.

If additional pain medication is needed after the administration of the total daily dose of Metacam Oral Suspension, a non-NSAID or noncorticosteroid class of analgesia should be considered. Consider appropriate washout times when switching from corticosteroid use or from one NSAID to another in dogs. Commonly used protein-bound drugs include cardiac, anticonvulsant and behavioral medications. Drug compatibility should be monitored in patients requiring adjunctive therapy.

The effect of cyclo-oxygenase inhibition and the potential for thromboembolic occurrence or a hypercoagulable state has not been studied. Dogs: A field study involving dogs was conducted.

Based on the results of this study, GI abnormalities vomiting, soft stools, diarrhea, and inappetance were the most common adverse reactions associated with the administration of meloxicam. The following table lists adverse reactions and the numbers of dogs that experienced them during the study.

Dogs may have experienced more than one episode of the adverse reaction during the study. In foreign suspected adverse drug reaction SADR reporting, adverse reactions related to meloxicam administration included: auto-immune hemolytic anemia 1 dogthrombocytopenia 1 dogpolyarthritis 1 dognursing puppy lethargy 1 dogand pyoderma 1 dog.

The following adverse reactions are based on post-approval adverse drug event reporting. The categories are listed in decreasing order of frequency by body system:.

Gastrointestinal: vomiting, diarrhea, melena, gastrointestinal ulceration. Death has been reported as an outcome of the adverse events listed above. Acute renal failure and death have been associated with the use of meloxicam in cats.

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Owners should be advised of the potential for adverse reactions and be informed of the clinical signs associated with NSAID intolerance. Adverse reactions may include vomiting, diarrhea, lethargy, decreased appetite and behavioral changes.

Dog owners should be advised when their pet has received a meloxicam injection. Dog owners should contact their veterinarian immediately if possible adverse reactions are observed, and dog owners should be advised to discontinue Metacam therapy.A clear, yellow solution containing 5 mg meloxicam per mL. Ethanol dehydrated Ph. Meloxicam is a nonsteroidal anti-inflammatory drug NSAID of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, analgesic and antipyretic effects.

Maximum plasma concentrations are obtained after approximately 1. There is a linear relationship between the dose administered and plasma concentration observed in the therapeutic dose range. The volume of distribution is 0. Meloxicam is predominantly found in plasma and is also a major biliary excretion product whereas urine contains only traces of the parent compound. Meloxicam is metabolized to an alcohol, an acid derivative and to several polar metabolites.

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All major metabolites have been shown to be pharmacologically inactive. Meloxicam is eliminated with a half-life of 15 hours cat and 24 hours dog. It is indicated for the alleviation of inflammation and pain in both acute and chronic musculo-skeletal disorders in dogs and also for the control of perioperative pain following orthopedic and soft tissue surgery in dogs and cats.

Control of Perioperative Pain: Dogs: Single intravenous or subcutaneous injection at a dosage of 0. Cats: Single subcutaneous injection at a dosage of 0. Give the lowest effective dose; giving a dose of 0. Do not exceed the recommended dose see Contraindications and Cautions sections. The use of parenteral fluids during surgery should be considered to reduce the risk of renal toxicity when using NSAIDs perioperatively.

Do not administer concurrently, other steroidal or nonsteroidal anti-inflammatory drugs NSAIDsaminoglycoside antibiotics or anti-coagulant agents. Pre-treatment with other steroidal or nonsteroidal anti-inflammatory drugs NSAIDs may result in additional or increased adverse effects and accordingly a treatment-free period with such drugs should be observed for at least 24 hours before commencement of treatment depending on the pharmacokinetic properties of the products used previously.

What Can I Give My Dog For Pain - Ask the Expert - Dr David Randall

Cautions: Use only as a single injection in cats. Particular care should be taken with regard to accuracy of dosing in cats. The safe use of this drug has not been established in breeding, pregnant or lactating animals; the potential benefits vs. Do not exceed the stated dose. In case of overdosing, symptomatic treatment should be initiated. Perioperative use requires careful assessment of risks and benefits for each individual patient. Increased risks of drug intolerance may occur in patients already debilitated or highly stressed, when there is concurrent use of other drugs premedication, anaesthetics which may lower blood pressure or increase the risk of renal or hepatic toxicity or in cases where there is surgical blood loss resulting in reduced tissue perfusion.

Animals being treated with meloxicam should be monitored for the occurrence of adverse effects as susceptibility varies with the individual.

Meloxicam Solution for Injection

Adverse reactions reported with the NSAID class of drugs include gastrointestinal signs, renal and hepatic toxicity as well as hematological, neurological and dermatological abnormalities. If gastrointestinal or other adverse effects occur, treatment should be discontinued. The most common adverse reactions reported involve the gastrointestinal tract in the dog inappetence, vomiting, diarrhea, potential ulceration and the renal system in the cat elevated creatinine and BUN, acute renal failure.

As for all NSAIDs, use in any dog less than 6 weeks of age or cat less than 4 months of age or in debilitated aged animals may involve additional risk.

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If use in such animals cannot be avoided, a reduced dosage and careful clinical management may be required. When administering any NSAID, appropriate laboratory testing to establish hematological and serum biochemical baseline data is recommended prior to use. Appropriate monitoring procedures should be employed during all surgical procedures, particularly with cats. Commonly used protein-bound drugs include cardiac, anticonvulsant and behavioural medications.

Drug compatibility should be monitored in patients requiring adjunctive therapy.Warning: Repeated use of meloxicam in cats has been associated with acute renal failure and death. Do not administer additional injectable or oral meloxicam to cats.

See Contraindications, Warnings, and Precautions for detailed information. Each mL of this sterile product for injection contains meloxicam 5. Carefully consider the potential benefits and risk of meloxicam injection and other treatment options before deciding to use meloxicam injection. Use the lowest effective dose for the shortest duration consistent with individual response.

metacam injection for dogs

Not for use in humans. Keep this and all medications out of reach of children.

Metacam for Dogs: A Guide on Uses, Dosage & Side Effects

Consult a physician in case of accidental ingestion by humans. For IV or SQ injectable use in dogs.

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Appropriate laboratory testing to establish hematological and serum biochemical baseline data is recommended prior to, and periodically during use of any NSAID in dogs. Meloxicam is not recommended for use in dogs with bleeding disorders, as safety has not been established in dogs with these disorders.

Safety has not been established for intramuscular IM administration in dogs. As a class, cyclo-oxygenase inhibitory NSAIDs may be associated with gastrointestinal, renal and hepatic toxicity. Sensitivity to drug-associated adverse events varies with the individual patient.

Concurrent administration of potentially nephrotoxic drugs should be carefully approached. NSAIDs may inhibit the prostaglandins that maintain normal homeostatic function. Such anti-prostaglandin effects may result in clinically significant disease in patients with underlying or pre-existing disease that has not been previously diagnosed. If additional pain medication is needed after the administration of the total daily dose of meloxicam oral suspension, a non-NSAID or noncorticosteroid class of analgesia should be considered.

Consider appropriate washout times when switching from corticosteroid use or from one NSAID to another in dogs. Commonly used protein-bound drugs include cardiac, anticonvulsant and behavioral medications.These are usually mild, but may be serious. If side effects occur, pet owners should halt therapy and contact their veterinarian. Pets should be evaluated for pre-existing conditions and currently prescribed medications prior to treatment with METACAM, then monitored regularly while on treatment.

The safe use of METACAM in dogs younger than 6 months of age, dogs used for breeding, or in pregnant or lactating bitches has not been evaluated. Please refer to the package insert for complete product information. Important Safety Information for Cats: Repeated use of meloxicam in cats has been associated with acute renal failure and death.

Do not administer a second dose of meloxicam. As a class, cyclo-oygenase inhibitory NSAIDs may be associated with gastrointestinal, kidney, or liver side effects. To ensure accurate dosing, the use of a 1 mL graduated syringe is recommended. Page content jump to main navigation jump to meta navigation. Dogs Indicated in dogs for the control of pain and inflammation associated with osteoarthritis Cats Indicated in cats for the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration when administered prior to surgery.

Sub-Q and IV injection options for timely relief of pain and inflammation associated with osteoarthritis in dogs — Achieve peak blood levels rapidly with IV administration 3 — Reach peak blood levels at 2. Safety Information Important Safety Information for Cats: Repeated use of meloxicam in cats has been associated with acute renal failure and death. Joseph, Missouri Company About History Careers Newsroom.

Species Equine Pet Poultry Swine. Connect twitter facebook youtube. All rights reserved.Metacam active ingredient meloxicam is a nonsteroidal anti-inflammatory drug NSAID considered safe for treating joint pain, stiffness, and swelling caused by arthritis in small, medium, and large dogs.

It may also be used for pain relief in dogs just out of surgery, spaying or neutering, tooth extraction, or those suffering from cancer [7]. It works in dogs by regulating pain and targeting the inflammation-causing enzymes, specifically the COX-2 enzyme. Metacam for Dogs. Liquid suspension, injection [3] Metacam meloxicam dosage for dogs: How much to give Never try this medication without consulting a vet, and follow the prescription to a T. The usually recommended dose is a single administration of 0.

Make sure that smaller dogs do not get overdosed, and to ensure that, put the oral suspension only in their food, never directly into their mouth [3]. Always shake the product well before administering [5]. The effects of Metacam peak around 8 hours after administration, and lasts for up to 24 hours [9]. All these side effects may make your dog tired or sleepy, while in some cases, they cause restlessness and panting.

If any of the side-effects mentioned above persist even after they have been addressed by the vet, your dog might have had an overdose. Your email address will not be published. All rights reserved. Reproduction in whole or in part without permission is prohibited.

By staff Last Updated : 30th June Related Articles Seborrhea in Dogs. Doxycycline for Dogs. Mexiletine for Dogs. Leave a Reply Cancel reply Your email address will not be published.

Pages Contact Us About Us.It is available only as a prescription medication in the form of tablets, injectables, and liquid. Metacam for dogs is given to relieve pain, fever, swelling, muscle injuries, and joint stiffness.

The drug contains 1. It is available as an oral suspension in form of 10, 32, or ml plastic squeeze bottle. It is yellow in color and smells like honey. It is also available in form of 7.

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It is usually prescribed by a licensed veterinarian though it has not been officially approved for veterinary use. Meloxicam is generally prescribed as a relief medication for pain, inflammation, and fever in dogs. It acts by inhibiting an enzyme called cyclooxygenase COX which is responsible for converting arachidonic acid to prostaglandins. Prostaglandins are hormones that mediate inflammatory responses in the body after cell injury.

Signs of inflammation include pain, redness, swelling, fever heat and loss of function in the affected area. They stimulate dilation of blood vessels thus causing an increase in blood supply to affected organs which is often seen as redness. Such responses also cause the release of inflammatory cells which leads to pain and swelling and consequently loss of function of affected body organs and tissues.

By inhibiting COX, prostaglandins are subsequently reduced therefore halting the process of inflammation. Metacam is long acting. This means that its therapeutic effect takes action slowly after the initial dose but is maintained over a period of time. An injectable form of the drug is also available but mostly used after surgical procedures to alleviate post-operative pain and swelling.

The initial dose is at 0. This is done using a drop dispenser or syringe which is graduated according to the dosage in milligrams per kilogram. It is also available in the form of tablets at a concentration of 7.

The medication should be shaken well before use. Thereafter the owner should pull the plunger of the syringe to draw the required amount of medication depending on the weight of the dog and dispense it into a bowl of food.

You should make sure all the food is eaten to avoid under-dosage. Dogs should be well hydrated throughout the treatment period by providing an ample supply of water. This is done mostly in puppies or dogs weighing less than 10 pounds. In big dogs, the medication is better administered directly into the mouth.

Improvement in symptoms is seen within 3 to 4 days. Treatment should be discontinued after 10 days. Like other forms of medication, administration of meloxicam comes with its share of side effects.

These include:. In some cases, dogs may exhibit an allergic reaction to meloxicam which may lead to an anaphylactic shock and death.Whether relieving the pain of osteoarthritis in large or small breed dogs or treating pain preemptively in cats prior to surgery, METACAM provides highly effective pain management that's rewarding for patients, practitioners, and owners alike.

As a class, cyclo-oxygenase inhibitory NSAIDs may be associated with gastrointestinal, kidney, or liver side effects. These are usually mild, but may be serious. If side effects occur, pet owners should halt therapy and contact their veterinarian. Pets should be evaluated for pre-existing conditions and currently prescribed medications prior to treatment with METACAM, then monitored regularly while on treatment.

Please refer to the package insert for complete product information. CATS: The safe use of Metacam Solution for Injection in cats younger than 4 months of age, cats used for breeding, or in pregnant or lactating queens has not been evaluated. Repeated use of meloxicam in cats has been associated with acute renal failure and death. Do not administer a second dose of meloxicam.

Metacam 0.5% Injection (Canada)

If side effects occur, dog owners should halt therapy and contact their veterinarian. Dogs should be evaluated for pre-existing conditions and currently prescribed medications prior to treatment with METACAM, then monitored regularly while on therapy.

metacam injection for dogs

Concurrent use with another NSAID, corticosteroid, or nephrotoxic medication should be avoided or monitored closely. Page content jump to main navigation jump to meta navigation. Company About History Careers Newsroom.

metacam injection for dogs

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